Generally speaking, good plots are about problems that mean a lot to the characters. If a problem is trivial, then neither the protagonist nor the reader has a reason to get worked up about it. You want your readers to get worked up about your novel. So you must give your protagonist a goal that matters.
One sign that a problem or goal matters to the protagonist is that he/she is willing to make sacrifices or suffer pain in order to achieve it. Such sacrifices are called Costs.
Classic examples of Costs include the hard-boiled detective who gets beaten up at some point in his investigation, or the heroic tales in which the hero must suffer pain or injury or give up a cherished possession to reach his goal. However, Costs can come in many other ways. Protagonists can be asked to give up their pride, self-respect, money, security, an attitude, an idealized memory, the life of a friend, or anything else they hold dear. If you make the costs steep and illustrate how hard the sacrifice is for the protagonist, the reader will feel that the protagonist deserves to achieve the goal.
In the case of our female executive, perhaps she must give up a promotion she has worked hard for because it would require her to travel so much that she would have no chance of settling down and raising a family.
Make a list of possible Costs your protagonist might be forced to endure in order to achieve the Story Goal. Again, just choose one idea to include in your plot outline for now.